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發(fā)布日期:2019-11-07 瀏覽次數(shù):6645

Intermediates List
Usage Product CAS No. Documentation
 Lamivudine L-Menthyl glyoxylate monohydrate (L-MGH)  111969-64-3  Technical Package
(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexyl ester (HME)  147126-62-3  Technical Package
(2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (CME)  147027-10-9  DMF/US FDA
(2R,5S)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- 2-(1H)-pyrimidinone salicylate (Lamivudine Salicylate)  173522-96-8  Technical Package
 Ritonavir ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate (NCT)  144163-97-3  Technical Package
N-[2-Isopropylthiazol-4-ylmethyl (methyl)-carbamoyl]-L-valine
(MTV-III)
 154212-61-0  Technical Package
(2S,3S,5S)-5-t-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane 1/2 succinate salt (BDH succinate salt)  183388-64-9  Technical Package
(2S,3S,5S)-5-t-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane (BDH PURE)  144163-85-9  Technical Package
 Cobicistat ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate (NCT)  144163-97-3  Technical Package
2-Isopropyl-4(((N- Methyl)amino) methyl)thiazole Dihydrochloride (MTV 2HCl)  1185167-55-8  Technical Package
 Entecavir (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)-diphenylmethyl] amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl) cyclopentanol (Ent-V)  142217-78-5  Technical Package
6-(Benzyloxy)-9-((1S,3R,3S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine (Ent-VII)  142217-80-9  Technical Package
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)- 2-methylenecyclopentyl]-6H-
purin-6-one (Ent-VIII)
 142217-81-0  Technical Package
 Emtricitabine (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl-1-yl)-[1,3] oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexyl ester (FCME)  764659-72-5  Technical Package
 Tenofovir
 Disoproxil
 Fumarate
(R)-9-[2-(Phosphonomethoxy)propyl]adenine (PMPA)
 147127-20-6  Technical Package

 Bedaquiline

 Fumarate

3-Benzyl-6-bromo-2-methoxyquinoline (BBMQ)  654655-69-3
 --
3-Dimethylamino-1-(naphthalen-1-yl) propan-1-one hydrochloride (DMNP)  5409-58-5
 --
 Lopinavir N-(4-Amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)-3-methyl-2-(2-oxo-tetrahydro-pyrimidin-1-yl)-butyramide 5-oxopyrrolidine-2-carboxylic acid (THP)  192726-06-0  --
 Tenofovir

 Alafenamide

 Fumarate

(S)-Isopropyl-2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)-phosphoryl)amino)propanoate (TA)  379270-37-8  --
9-[(R)-2-(phenylphosphonomethoxy) propyl]adenine (PPMPA)  379270-35-6  --
 Dolutegravir (4R,12aS)-3,4,6,8,12,12a-Hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid  1335210-34-8  --
(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide  1335210-35-9  --

 Selegiline

 Hydrochloride

N,N-dimethyl-N'-(1-phenylpropan-2-yl)-Sulfamide  1875882-12-4  --
(2R)-1-phenyl-N-prop-2-ynylpropan-2-amine hydrochloride  115586-38-4  --
R-(-)-N-Demethyl Deprenyl  56862-28-3  --
R & D List
 Abacavir Sulfate (1R,4S)-4-amino-2-Cyclopentene-1-methanol hydrochloride  287717-44-6  --
2-amino-4,6-dichloro-5-formamidopyrimidine  171887-03-9  --
 Obeticholic Acid 3alpha-Hydroxy-7-oxo-5beta-cholic acid  4651-67-6  --
Methyl 7-keto-3alpha-hydroxy-5beta-cholanoate  10538-59-7  --
(R)-methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-(tert-butyldimethylsilyloxy)-10,13-dimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate  336099-76-4  --
(R)-methyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate  1516887-31-2
(R)-methyl 4-((3R,6S)-6-ethyl-hexadecahydro-3-hydroxy-10,13-dimethyl-7-oxo-1H-cyclopental[a]phenanthren-17-yl)pentanoate  1654780-32-1
(3alpha,5beta,6alpha)-6-Ethyl-3-hydroxy-7-oxocholan-24-oic acid  915038-26-5  --
 Rilpivirine 4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile  189956-45-4  --
4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile  244768-32-9
4-Iodo-2,6-dimethylaniline  4102-53-8  --
3-(4-amino-3,5-dimethylphenyl)prop-2-enamide  500292-92-2
(E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile hydrochloride  661489-23-2  --
* Patent-protected area, not to be sold.
www.yangonquote.com / info@bcpharm.com / WeChat: bcpharm

Intermediates List
Usage Product CAS No. Documentation
Lamivudine L-Menthyl glyoxylate monohydrate (L-MGH) 111969-64-3 Technical Package
(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexyl ester (HME) 147126-62-3 Technical Package
(2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester (CME) 147027-10-9 DMF/US FDA
(2R,5S)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- 2-(1H)-pyrimidinone salicylate (Lamivudine Salicylate) 173522-96-8 Technical Package
Ritonavir ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate (NCT) 144163-97-3 Technical Package
N-[2-Isopropylthiazol-4-ylmethyl (methyl)-carbamoyl]-L-valine
(MTV-III)
154212-61-0 Technical Package
(2S,3S,5S)-5-t-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane 1/2 succinate salt (BDH succinate salt) 183388-64-9 Technical Package
(2S,3S,5S)-5-t-Butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane (BDH PURE) 144163-85-9 Technical Package
Cobicistat ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate (NCT) 144163-97-3 Technical Package
2-Isopropyl-4(((N- Methyl)amino) methyl)thiazole Dihydrochloride (MTV 2HCl) 1185167-55-8 Technical Package
Entecavir (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)-diphenylmethyl] amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl) cyclopentanol (Ent-V) 142217-78-5 Technical Package
6-(Benzyloxy)-9-((1S,3R,3S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine (Ent-VII) 142217-80-9 Technical Package
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)- 2-methylenecyclopentyl]-6H-
purin-6-one (Ent-VIII)
142217-81-0 Technical Package
Emtricitabine (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl-1-yl)-[1,3] oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexyl ester (FCME) 764659-72-5 Technical Package
Tenofovir
Disoproxil
Fumarate
(R)-9-[2-(Phosphonomethoxy)propyl]adenine (PMPA)
147127-20-6 Technical Package

Bedaquiline

Fumarate

3-Benzyl-6-bromo-2-methoxyquinoline (BBMQ) 654655-69-3
 --
3-Dimethylamino-1-(naphthalen-1-yl) propan-1-one hydrochloride (DMNP) 5409-58-5
 --
Lopinavir N-(4-Amino-1-benzyl-3-hydroxy-5-phenyl-pentyl)-3-methyl-2-(2-oxo-tetrahydro-pyrimidin-1-yl)-butyramide 5-oxopyrrolidine-2-carboxylic acid (THP) 192726-06-0  --
Tenofovir

Alafenamide

Fumarate

(S)-Isopropyl-2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)-phosphoryl)amino)propanoate (TA) 379270-37-8  --
9-[(R)-2-(phenylphosphonomethoxy) propyl]adenine (PPMPA) 379270-35-6  --
Dolutegravir (4R,12aS)-3,4,6,8,12,12a-Hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid 1335210-34-8  --
(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 1335210-35-9  --

Selegiline

Hydrochloride

N,N-dimethyl-N'-(1-phenylpropan-2-yl)-Sulfamide 1875882-12-4  --
(2R)-1-phenyl-N-prop-2-ynylpropan-2-amine hydrochloride 115586-38-4  --
R-(-)-N-Demethyl Deprenyl 56862-28-3  --
R & D List
Abacavir Sulfate (1R,4S)-4-amino-2-Cyclopentene-1-methanol hydrochloride 287717-44-6  --
2-amino-4,6-dichloro-5-formamidopyrimidine 171887-03-9  --
Obeticholic Acid 3alpha-Hydroxy-7-oxo-5beta-cholic acid 4651-67-6  --
Methyl 7-keto-3alpha-hydroxy-5beta-cholanoate 10538-59-7  --
(R)-methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-(tert-butyldimethylsilyloxy)-10,13-dimethyl-7-oxo-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 336099-76-4  --
(R)-methyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate 1516887-31-2
(R)-methyl 4-((3R,6S)-6-ethyl-hexadecahydro-3-hydroxy-10,13-dimethyl-7-oxo-1H-cyclopental[a]phenanthren-17-yl)pentanoate 1654780-32-1
(3alpha,5beta,6alpha)-6-Ethyl-3-hydroxy-7-oxocholan-24-oic acid 915038-26-5  --
Rilpivirine 4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile 189956-45-4  --
4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile 244768-32-9
4-Iodo-2,6-dimethylaniline 4102-53-8  --
3-(4-amino-3,5-dimethylphenyl)prop-2-enamide 500292-92-2
(E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile hydrochloride 661489-23-2  --
* Patent-protected area, not to be sold.
www.yangonquote.com / info@bcpharm.com / WeChat: bcpharm